Web23 okt. 2024 · CARDIO-TTRansform: A Study to Evaluate the Efficacy and Safety of Eplontersen (Formerly Known as ION-682884, IONIS-TTR-LRx and AKCEA-TTR-LRx) in Participants With Transthyretin-Mediated Amyloid Cardiomyopathy (ATTR CM) The safety and scientific validity of this study is the responsibility of the study sponsor and … WebIonis is focused on delivering RNA-targeted therapeutics with transformational potential. Our antisense oligonucleotide drug discovery platform has transformed the lives of patients with devastating diseases, including SMA, hATTR, and FCS. We have the potential to treat many additional diseases where other therapeutic approaches have proven ...
GSK initiates Phase 1 study of IONIS-HBV-LRx
Web10 jan. 2024 · GENOME—Empirico said on Thursday that it has formed a drug discovery alliance with antisense therapeutics firm Ionis Pharmaceuticals. As part of the deal, Ionis has taken a $10 million stake in Empirico, which also announced the close of a $17 million Series A-2 financing round. Under the terms of the deal, San Diego-based … Web24 nov. 2024 · Methods: This multicenter study enrolled 49 patients receiving HD in 2 parts. First, 6 participants (pharmacokinetics [PK] cohort) received 1 open-label 300 mg dose of IONIS-FXI Rx both before and after HD. Subsequently, 43 participants were treated in a double-blind, randomized design with 200 mg or 300 mg IONIS-FXI Rx or placebo for 12 … chs office locations
Antisense oligonucleotide therapy rescues disturbed brain …
Web17 mrt. 2024 · Aandeel Ionis Pharmaceuticals OTC:IONS.Q, US4622221004 Vertraagde koers Settlement koers (usd) 35,180 17 mrt 2024 21:00 Verschil +0,180 (+0,51%) … Webp Using his fellowship training in spinal surgery for adult and pediatric patients, Ioannis Alexander Avramis, MD, board-certified orthopedic surgeon, focuses on the comprehensive treatment of spinal deformity of both patient populations. Dr. Avramis is Director of the Baylor Scott White Spine Scoliosis Center at Baylor University Medical … Web26 okt. 2024 · In 2016, the Food and Drug Administration approved the first successful antisense drug, nusinersen, to treat spinal muscular atrophy, a muscle wasting disease. description of learning styles